Vinyl chloride, also known as vinyl chloride, with the chemical formula C2H3Cl, is an organic compound that is an important monomer in polymer chemistry.
On October 27, 2017, the World Health Organization's International Agency for Research on Cancer published a preliminary list of carcinogens for reference, and vinyl chloride is in the list of Group 1 carcinogens.

It is mainly used in the manufacture of homopolymers and copolymers of polyvinyl chloride. It can also be copolymerized with vinyl acetate and butadiene, and is used as an extractant for dyes and fragrances. Used as a copolymer monomer of various polymers, an important raw material for the plastics industry, and as a freezing agent. Also used as extractant for dyes and fragrances.

Exposure opportunities. In the production process of both vinyl chloride and polyvinyl chloride, there is a possibility of exposure to vinyl chloride, especially in the cleaning of polymerization kettles for the production of polyvinyl chloride, and the possibility of chronic vinyl chloride poisoning is greatest for kettle cleaners. When applying polyvinyl chloride resin or copolymers containing vinyl chloride after melting to make various plastic products. Vinyl chloride monomer is released, and sometimes the concentration of vinyl chloride in the air of the operating environment is very high, which can easily cause poisoning.

Clinical manifestations of poisoning: Acute poisoning. In mild poisoning, the patient appears dizziness, headache, nausea, chest tightness, drowsiness, staggering gait, etc.; in severe poisoning, confusion, or drowsiness or even coma, convulsions and more serious cases can cause death.

Chronic poisoning is mainly manifested as neurasthenia syndrome, liver damage, digestive dysfunction, osteolysis of the extremities, skin damage, etc. This product is a carcinogen can cause hepatic angiosarcoma.

Nervous system: manifestation of vertigo, headache, weakness, insomnia or drowsiness, dreaminess, easy to wake up, memory loss, irritability, etc.. Sometimes it presents with head heaviness, disorientation, change of temperament, soreness of limbs, sweaty palms fingers, tongue and eyelid tremors.

Digestive system:Loss of appetite nausea, erratic, abdominal distension, constipation, etc. Hepatomegaly abnormal liver function.

Skin changes with dry ruptured skin, papules, acne, or changes such as keratinization of palms and thinning of nails.

Skin end drop bone is more common in clear kettle workers made of polyvinyl chloride. The manifestation is tingling or soreness in the fingertips. X-rays of the hand may show hemimelia or osteolytic defects on one or more edges of the end phalanges, and sometimes the finger joints may be misaligned.

Carcinogenesis: Vinyl chloride causes hepatic angiosarcoma and has been listed as a national statutory occupational disease.